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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: CDK14 All Species: 40.61
Human Site: S282 Identified Species: 68.72
UniProt: O94921 Number Species: 13
    Phosphosite Substitution
    Charge Score: -0.15
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O94921 NP_036527.1 469 53057 S282 F G L A R A K S V P S H T Y S
Chimpanzee Pan troglodytes XP_519189 469 53035 S282 F G L A R A K S V P S H T Y S
Rhesus Macaque Macaca mulatta XP_001102520 469 53072 S282 F G L A R A K S V P S H T Y S
Dog Lupus familis XP_532455 469 53036 S282 F G L A R A K S V P S H T Y S
Cat Felis silvestris
Mouse Mus musculus O35495 469 52977 S282 F G L A R A K S V P S H T Y S
Rat Rattus norvegicus O35831 523 59414 S339 F G L A R A K S V P T K T Y S
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001516045 337 37621 K176 I R E A S L L K G L K H A N I
Chicken Gallus gallus XP_418647 773 84016 S586 F G L A R A K S V P S H T Y S
Frog Xenopus laevis Q6DJM7 435 49211 S248 F G L A R A K S V P S H T Y S
Zebra Danio Brachydanio rerio Q1RLU9 418 47889 G254 R P P D V L M G S T D Y S T A
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_523904 522 59750 S352 F G L A R A K S V P S H T Y S
Honey Bee Apis mellifera XP_624994 494 56118 S315 F G L A R A K S V P S H T Y S
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana P24100 294 34012 L133 R D L K P Q N L L I D R R T N
Baker's Yeast Sacchar. cerevisiae P17157 305 34888 R144 Q N L L I N K R G Q L K L G D
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.3 99.7 99.1 N.A. 98.5 43 N.A. 60.7 58.5 85.2 51.5 N.A. 48.4 50 N.A. N.A.
Protein Similarity: 100 99.5 99.7 100 N.A. 99.3 59 N.A. 63.3 59.5 89.3 63.1 N.A. 61.2 63.3 N.A. N.A.
P-Site Identity: 100 100 100 100 N.A. 100 86.6 N.A. 13.3 100 100 0 N.A. 100 100 N.A. N.A.
P-Site Similarity: 100 100 100 100 N.A. 100 93.3 N.A. 13.3 100 100 20 N.A. 100 100 N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. 30.7 28.5 N.A.
Protein Similarity: N.A. N.A. N.A. 42.8 43.9 N.A.
P-Site Identity: N.A. N.A. N.A. 6.6 13.3 N.A.
P-Site Similarity: N.A. N.A. N.A. 20 13.3 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 79 0 72 0 0 0 0 0 0 8 0 8 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 8 0 8 0 0 0 0 0 0 15 0 0 0 8 % D
% Glu: 0 0 8 0 0 0 0 0 0 0 0 0 0 0 0 % E
% Phe: 72 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 72 0 0 0 0 0 8 15 0 0 0 0 8 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 72 0 0 0 % H
% Ile: 8 0 0 0 8 0 0 0 0 8 0 0 0 0 8 % I
% Lys: 0 0 0 8 0 0 79 8 0 0 8 15 0 0 0 % K
% Leu: 0 0 86 8 0 15 8 8 8 8 8 0 8 0 0 % L
% Met: 0 0 0 0 0 0 8 0 0 0 0 0 0 0 0 % M
% Asn: 0 8 0 0 0 8 8 0 0 0 0 0 0 8 8 % N
% Pro: 0 8 8 0 8 0 0 0 0 72 0 0 0 0 0 % P
% Gln: 8 0 0 0 0 8 0 0 0 8 0 0 0 0 0 % Q
% Arg: 15 8 0 0 72 0 0 8 0 0 0 8 8 0 0 % R
% Ser: 0 0 0 0 8 0 0 72 8 0 65 0 8 0 72 % S
% Thr: 0 0 0 0 0 0 0 0 0 8 8 0 72 15 0 % T
% Val: 0 0 0 0 8 0 0 0 72 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 8 0 72 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _